Based on the latest research into the biology of the skin

The MosaicLife approach recognises the role the mast cell plays in causing inflammation and in the wound healing process. This page will give you more understanding about the effects of inflammation on your skin, nails and mouth during your Radiotherapy and Chemotherapy treatment.

Inflammation of the skin

Inflammation is the body’s immediate response to infection or injury. Injury can include radiotherapy and chemotherapy. The classic signs of inflammation are redness, swelling, heat and pain (including itch).  The immune system of the skin is regulated by chemical mediators such as cytokines and bioactive lipids (or fatty acids).

Fatty acids have long been known to play a major role in regulating the immune system and their activity in skin inflammation is particularly prominent. Fatty acids are are also very important for the health and maintenance of the skin barrier (epidermis).

Mast cells are key to the inflammatory reaction. They are among the first cells to trigger the physiological defense process of the body.

The role of the mast cell

Mast cells are immune cells which line the surfaces of the body including the skin and mucosa (such as the lining of the mouth). They release biological mediators that trigger inflammation (redness, swelling and pain) and stimulate the nerve pathways, causing itch.

Mast cellInflammation is normally a short-lived, helpful and natural part of the body’s defence system. However, with radiotherapy or chemotherapy treatment, the mast cell becomes over stimulated and releases all its damaging contents at the same time. This amplifies the harm caused to the skin or mucosal lining.

Nature’s helpful counter measures

Fortunately, nature also puts in place counter-measures to control the excessive inflammatory activity of the mast cell. These measures come in the form of fatty acids and fatty acid amides, such as palmitoylethanolamide (PEA for short). The increased stress on the skin caused by anticancer therapy means the body can no longer produce enough of these substances naturally and supplementation is needed.

(F.A.G.) Fatty Acid Group

Fatty acids give each immune cell in the skin the biological material it needs to be able to produce its own down-regulators of inflammation. Research continues to grow about the important role that essential fatty acids play in the skin immune system

The MosaicLife products contain a specific and patented group of essential fatty acids called F.A.G. (Fatty Acid Group). Up to 9 fatty acids (like Palmitic acid, Oleic acid, Stearic acid, Linoleic acid and Azelaic acid) may be combined to produce the correct balance to support the skin.

F.A.G. (Fatty Acid Group) - MosaicLife products are based on the latest research into the biology of the skin

With the MosaicLife products it is possible to supplement these helpful lipid compounds. This puts the body back into natural balance, soothes the inflamed tissue and the resulting skin reaction is reduced.

F.A.G. is patented by Again Life Italia SRL, Italy.